Facial Serum

30 ml

This product is usually paired with a cream. It’s simple yet effective because it contains a series of active ingredients that are very efficient against ageing.


SKU: M7 Category:

Facial Serum's Characteristics

Hyaluronic acid which maintains and increases skin hydration.

Centella asiatica acts on the inflammation caused by ageing and strengthens microcirculation.

Echinacea acts on inflammation and is an immunostimulant.

M7 Facial Serum has been widely tested after invasive treatments such as fractional radio frequency by soothing the skin and decreasing inflammation and by favouring a fast cicatrization.

Facial Serum’s Active ingredients:

Assuming that aging is linked to general microinflammation, these two molecules, gotu kola, and echinacea, act in synergy against inflammation thus slowing down the aging process.

Centella Asiatica increases collagen formation because it stimulates the production of TGF BETA which is the growth factor of hyaluronic acid and chondroitin sulfate. These two molecules are the matrix of the dermis, the pillow where the epidermis rests. They increase the skin’s elasticity and improve vascularization.

Echinacea has an anti-hyaluronidase effect on the skin. Hyaluronidase is an enzyme that degrades hyaluronic acid and therefore if we contrast the lytic effect of this enzyme, we will have smoother skin with fewer wrinkles and less aged.

The combination of these two molecules guarantees its effectiveness specifically against aging. By stimulating collagen production, they reduce inflammation and inhibit the factors that degrade the matrix, which is composed of hyaluronic acid and collagen.

Elastin gives a velvety and cosmetically pleasant effect.

Hyaluronic acid is a mucopolysaccharide belonging to the group of glycosaminoglycans (GAGs). It is an essential functional component of almost all tissues in vertebrate organisms. Chemically its molecular weight is normally around 1-5 million Daltons and is made up of an unbranched polysaccharide chain produced by the aggregation of thousands of disaccharide units, in turn formed by residues of glucuronic acid (glucose derivative) and N-acetylglucosamine.

In vivo all of the carboxylic groups of glucuronic acid and N-acetylglucosamine are completely ionized, giving the hyaluronic acid molecule high polarity and, consequently, high solubility in water. Due to this property hyaluronic acid surrounds itself with many water molecules reaching a high degree of hydration.
The rationale behind the use of hyaluronic acid in skin rejuvenation derives from its loss during the aging process.

In cosmetic formulations, the use of hyaluronic acid allows the creation of a film on the skin which prevents water loss and increases hydration. The skin constantly needs support in fighting dehydration factors.
Hyaluronic acid is a macromolecule capable of attracting and retaining water in the deepest layers of the dermis. To better understand what the effects of hyaluronic acid are on the skin, let’s think of a baby’s skin: soft, compact, elastic, and hydrated. A baby’s skin has a high content of hyaluronic acid. Unfortunately, our body’s hyaluronic acid supplies are not infinite and our body, due to the aging process, tends to produce less of it over time causing wrinkles and skin laxity. That’s why hyaluronic acid must be integrated into skincare.
Scientific studies and cosmetic tests have shown that with the application of hyaluronic acid, many of the deficits that would occur naturally can be significantly mitigated.
Hyaluronic acid has unique biological characteristics and in addition to the moisturizing factor, it also has anti-inflammatory properties. These properties are fundamental in supporting the structure and function of tissues such as the skin, blood vessels, extracellular matrix, and connective tissue.
There are several ways of conveying this precious element that can be used in cosmetic formulations that help to overcome the obstacle of the skin barrier, the most effective is the use of microspheres and liposomes.
The use of microspheres consists of the dehydration of hyaluronic acid and its dispersion in a fat-soluble solution.
Once put in an aqueous medium, this compound has the ability to absorb water and swell up, considerably increasing its volume up to about three times. When this form of hyaluronic acid is applied to the skin, particularly near wrinkles, it draws in water, increasing its volume and filling the wrinkle.
Another interesting method of delivery is liposomal spheres containing hyaluronic acid which are able to cross the stratum corneum. This system works by releasing hyaluronic acid in the deeper layers of the epidermis, which in turn performs a protective and repairing action on the skin.
When using precious ingredients like hyaluronic acid it’s necessary to formulate a good product where the active ingredients can penetrate in the most adequate way possible without being aggressive and therefore through a biocompatible delivery system that respects skin physiology.
This serum combines a high concentration of hyaluronic acid molecules and a system of excipients expertly developed to facilitate their penetration to the layers of the papillary dermis.


  • Nawrat P, Surazyski A, Karna E, Paka J A. The effect of hyaluronic acid on interleukin-1-induced deregulation of collagen metabolism in cultured human skin fibroblasts. Pharmacol Res 2005; 51:473–7.
  • Price R D, Berry M G, Navsaria H A. Hyaluronic acid: the scientific and clinical evidence. Journal of Plastic, Reconstructive & Aesthetic Surgery 2007; 60: 1110–1119
  • Tammi M I, Day A J, Turley E A. Hyaluronan and homeostasis: a balancing act. J Biol Chem 2002; 277:4581–4784.


Centella Asiatica extract is obtained from Asian Hydrocotile, a plant belonging to the Apiaceae family typical of Madagascar, India, Ceylon and Mauritius. Essentially, Asian Hydrocotyle is a healing plant that grows in humid and shady places, such as along waterways, marshy areas and in forests that see very little sunlight. Its characteristic are violet flowers and rounded leaves, arranged in a rosette.
It’s precisely the leaves that contain active ingredients that make Centella Asiatica a remedy used for the toning of blood vessels and healing of the skin. It’s thanks to these virtues that Centella Asiatica is also known as “Indian ginseng” and “tiger plant”: legend has it that tigers, when they suffered an injury they rubbed against it to heal.
Since ancient times Centella Asiatica has been used to cure skin diseases such as lupus and ulcerations. From this plant is possible to extract elements with phytotherapeutic power consisting mainly of triterpenes, asian acid, madecassic acid glycosides, asiaticoside and madecassoside.
This precious active ingredient is used in various preparations for dermo-cosmetic use aimed at the treatment of cellulite blemishes, improving the functionality of microcirculation and maintaining skin elasticity.


The “cica creams” (acronym of Centella asiatica) are considered a real Korean beauty remedy to give your skin a healthy appearance and above all erase the signs of aging. Centella asiatica possesses many healing and revitalising virtues. It promotes the formation of new layers of cells: thus accelerating the healing of first and second degree burns, dermatosis and eczema. It’s also an excellent ingredient in anti-wrinkle that prevent skin laxity.


Against wrinkles

Centella asiatica stimulates the formation of new collagen, it also increases skin tone, very useful against wrinkles and sagging skin. It also intervenes in the re-epithelialization of damaged tissues.
Dermatology studies have shown that the treatment of a with a centella asiatica cream significantly improves the density of the skin micro-reliefs and decreases the depth of wrinkles thanks to an increase in the synthesis of collagen.
The application of centella-based creams, in addition to stimulating the production of collagen thanks to fibroblasts (dermal cells), also increases skin fibronectin, an important structural protein for the maintenance of microcirculation.
This improves the structure of the skin as a whole, making it more turgid and compact.


Against Scars
Centella asiatica’s ability to repair damaged tissues makes it very useful as cicatrizing agent. The plant extract can be found in gels and creams and it can be applied directly on the scar. Thanks to its cicatrizing and re-epithelizing properties centella asiatica counteracts the loss of elasticity and the formation of wrinkles and stretch marks.


Centella Asiatica and photoaging
Due to all the properties previously discussed, centella asiatica is used as an anti-photoaging agent. Its elements have the ability to to significantly stimulate the synthesis of type I collagen, the quantities of which tend to grafually decrease with ageing, resulting in fragility not only cutaneous, but also vascular, with the related aesthetic and functional consequences.
All this has been experimentally confirmed by a recent trial conducted on 20 participants, in which the use of centella asiatica extracts, combined with viamin C, has guaranteed in six months of treatment a visible improvement in firmness, elasticity and hydration of the skin subjected to photoaging.
The researchers also investigated the cellular action of these elements, identifying the individual molecular variations induced for example by madecassoside, and also characterizing in detail all the biological mechanisms involved in the photo-protection and in the synthesis of type I collagen, thus completing the clinical and biological description of this plant.


Centella asiatica extracts have generally proved to be safe and well tolerated. Only rarely and in predisposed subjects the use of these extracts has transiently determined the onset of local allergic reactions and eczema. Centella asiatica in not suitable for people who are obviously allergic to it and have particulalry photosensitive light complexions.


  • Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Brzezińska M. Centella asiatica in cosmetology. Postepy Dermatol Alergol. 2013 Feb;30(1):46-9
  • James JT, Dubery IA. Pentacyclic triterpenoids from the medicinal herb, Centellaasiatica, Molecules. 2009 Oct 9;14(10):3922-41.


Echinacea root has valuable healing and cosmetic properties. It’s extracted from perennial herbaceous plants about one metre high with cylindrical rhizome and slightly reddish stems. There are two types: Angustifolia owes its name to narrow leaves, while the Purpurea has wider leaves. These plants are native to North America, Mexico, Louisiana, Florida.

The precious substance that is extracted from these plants contains polysaccharides that give the plant immunostimulating properties, for this reason it is used in herbal medicine to promote natural defenses, as it stimulates the immune system, thus supporting the body against infectious attacks.

In cosmetics, echinacea is used for the preparation of skin creams and lotions, with an immunostimulating, protective and anti-inflammatory action.
The healing property is based on the ability of the plant to accelerate regeneration.


Cosmetic Properties

Echinacea estract has a strong anti-hyaluronidasic activity (it inhibits the degradation of hyaluronic acid) and immunostimulant, re-epithelizing, firming, regenerating and elasticizing properties.

It accelerates the healing and re-epithelization processes at the dermis and epidermis levels, thus improving their hydration. All these properties make echinacea a valuable ingredient in the preparation of anti-ageing products.

In the last few years numerous studies, both experimental and clinical, have shown the effectiveness of echiancea extracts in:

  • The healing of ulcers and wounds thanks to the ability to activiate fibroblasts and enhance the synthesis of collagen fibres; protect the skin from the action of pathogens, enhancing the activity of immune system cells such as macrophages and Natural Killer cells.
  • Improvement of acne lesions by controlling the proliferation of microbial agents such as Proprionibacterium acnes.
  • Protection of the skin from the harmful action of ultraviolet radiation.
  • To control and facilitate the regression of autoimmune and inflammatory lesions.


The systemic and functional anti-aging action of Echinacea is therefore inevitably associated with the “aesthetic” one guaranteed by the correct activation of the immune system and its immediate effects on the skin, the first anatomical and functional barrier against harmful agents of microbial, viral, fungal, chemical and physical nature.


  • Mullins RJ, Heddle R. Ann, Adverse reactions associated with echinacea: the Australian experience. Allergy Asthma Immunol. 2002 Jan;88(1):42-51.
  • Speroni E, Govoni P, Guizzardi S, Renzulli C, Guerra MC. J, Anti-inflammatory and cicatrizing activity of Echinacea pallida Nutt. root extract Ethnopharmacol. 2002 Feb;79(2):265-72.

Other Products

Scrivici per maggiori informazioni o dettagli sui Prodotti